Description

Cyclopropanecarbonitrile, 2-(4-Methoxyphenyl)-, (1R,2R)-Rel- (9Ci) is a high-purity, chiral nitrile building block of significant interest in advanced organic synthesis. Its value lies in the stereochemically defined cyclopropane ring and functional handles, which are crucial for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily needed by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the discovery and production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique optical or electronic properties.
• Academic & Contract Research: A valuable tool for methodology development and complex natural product synthesis in academic and industrial research laboratories.

Basic Information

Product Name	Cyclopropanecarbonitrile, 2-(4-Methoxyphenyl)-, (1R,2R)-Rel- (9Ci)
CAS No.	301861-18-7
Molecular Formula	C11H11NO
Molecular Weight	173.21 g/mol
Synonyms	(1R,2R)-2-(4-Methoxyphenyl)cyclopropanecarbonitrile; rel-(1R,2R)-2-(4-Methoxyphenyl)cyclopropanecarbonitrile; (1R,2R)-2-(p-Methoxyphenyl)cyclopropanecarbonitrile; 2-(4-Methoxyphenyl)cyclopropanecarbonitrile (1R,2R)-isomer; (1R,2R)-2-(4-Methoxyphenyl)cyclopropanenitrile
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarbonitrile, 2-(4-Methoxyphenyl)-, (1R,2R)-Rel- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including chiral purity analysis, to ensure consistency and meet the exacting standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.