Description

Piperidine, 1-(2,2,3,3-Tetrafluoro-1-Oxopropyl)- (9Ci) is a specialized fluorinated piperidine derivative, a high-value building block in advanced organic synthesis. This compound is critical for introducing a unique tetrafluoropropionyl-substituted piperidine scaffold into target molecules, enabling the fine-tuning of physicochemical properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Acts as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research of advanced polymers and functional materials, where the fluorinated group can impart specific surface properties.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Piperidine, 1-(2,2,3,3-Tetrafluoro-1-Oxopropyl)- (9Ci)
CAS No.	300403-32-1
Molecular Formula	C8H11F4NO
Molecular Weight	213.17 g/mol
Synonyms	1-(2,2,3,3-Tetrafluoropropionyl)piperidine; 1-(Perfluoropropionyl)piperidine; N-(2,2,3,3-Tetrafluoropropionyl)piperidine; 2,2,3,3-Tetrafluoro-1-(piperidin-1-yl)propan-1-one; Piperidine, 1-(tetrafluoropropionyl)-; Tetrafluoropropionylpiperidine
EINECS	Contact for details

Quality Control

Our Piperidine, 1-(2,2,3,3-Tetrafluoro-1-Oxopropyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.