Description

n-[(1S,2S)-2-Amino-1,2-Diphenylethyl]-Benzenesulfonamide is a high-purity chiral sulfonamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its well-defined stereochemistry and functional groups, which enable the precise construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, especially for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Ligand: Used as a precursor or component in the synthesis of chiral ligands for transition metal-catalyzed asymmetric reactions.
• Chemical Research: Employed in academic and industrial R&D for studying reaction mechanisms and developing new synthetic methodologies involving sulfonamide chemistry.
• Fine Chemical Synthesis: A versatile building block for the production of specialty chemicals, agrochemicals, and other high-value compounds requiring specific stereochemistry.

Basic Information

Product Name	n-[(1S,2S)-2-Amino-1,2-Diphenylethyl]-Benzenesulfonamide
CAS No.	300345-91-9
Molecular Formula	C20H20N2O2S
Molecular Weight	352.45 g/mol
Synonyms	(1S,2S)-N-(2-Amino-1,2-diphenylethyl)benzenesulfonamide; (1S,2S)-1,2-Diphenyl-2-(phenylsulfonylamino)ethylamine; (S,S)-DPEN Sulfonamide; (1S,2S)-DPEN-Sulfonamide; Benzenesulfonamide, N-[(1S,2S)-2-amino-1,2-diphenylethyl]-; (S,S)-TsDPEN; (S,S)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine derivative
EINECS	Contact for details

Quality Control

Our n-[(1S,2S)-2-Amino-1,2-Diphenylethyl]-Benzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and residual solvent content. Our quality commitment supports applications requiring high-purity chiral intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.