Description

4-Hydroxylidocaine is a key pharmaceutical intermediate and metabolite of the local anesthetic lidocaine. This compound matters for its critical role in drug development, metabolism studies, and the synthesis of more complex bioactive molecules. It is primarily needed by research institutions, pharmaceutical manufacturers, and analytical laboratories focused on neuropharmacology, anesthetic development, and forensic toxicology.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of lidocaine derivatives and related anesthetic compounds.
• Metabolite Reference Standard: Used as an analytical standard in pharmacokinetic and metabolism studies of lidocaine in clinical and forensic toxicology.
• Biochemical Research: Employed in studies investigating sodium channel interactions and the metabolic pathways of aminoamide local anesthetics.
• Quality Control & Analytical Testing: Serves as a certified reference material (CRM) for HPLC, LC-MS, and GC-MS methods in pharmaceutical quality assurance labs.
• Academic Research: Utilized in university and institutional research projects exploring anesthetic mechanisms, drug design, and metabolic profiling.

Basic Information

Product Name	4-Hydroxylidocaine
CAS No.	39942-41-1
Molecular Formula	C14H22N2O2
Molecular Weight	250.34 g/mol
Synonyms	4-Hydroxylidocaine; 2-(Diethylamino)-N-(2,6-dimethyl-4-hydroxyphenyl)acetamide; 4'-Hydroxylidocaine; Lidocaine 4'-Hydroxy Metabolite; MEGX (Monoethylglycinexylidide) isomer; 2,6-Dimethyl-4-hydroxyacetanilide diethylamino derivative
EINECS	Contact for details

Quality Control

Our 4-Hydroxylidocaine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.