Description

N2-[(Vinyloxy)Carbonyl]-L-Asparagine is a specialized amino acid derivative where the asparagine side chain is protected by a vinyloxycarbonyl (Voc) group. This compound is a crucial protected building block in the synthesis of complex peptides and other bioactive molecules, offering selective deprotection under mild conditions. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced peptide chemistry and drug discovery programs.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key protected asparagine residue for the controlled assembly of peptide chains.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides and small proteins where selective side-chain protection is required.
• Pharmaceutical Intermediates: Acts as a critical precursor in the research and development of peptide-based therapeutics and APIs.
• Bioconjugation Chemistry: Employed in the modification of peptides and proteins for labeling or functionalization studies.
• Academic & Industrial R&D: A valuable reagent for chemists exploring new synthetic methodologies and peptide mimetics.
• Protecting Group Strategy: The Voc-protected asparagine is used in multi-step syntheses where orthogonal deprotection strategies are necessary.

Basic Information

Product Name	N2-[(Vinyloxy)Carbonyl]-L-Asparagine
CAS No.	39897-15-9
Molecular Formula	C8H12N2O5
Molecular Weight	216.19 g/mol
Synonyms	L-Asparagine, N-[(vinyloxy)carbonyl]-; N-Voc-L-asparagine; Nα-(Vinyloxycarbonyl)-L-asparagine; (2S)-2-[(Vinyloxycarbonyl)amino]-3-carbamoylpropanoic acid; N-[(Vinyloxy)carbonyl]asparagine; Voc-Asn-OH; 39897-15-9; N-VOC-L-ASN-OH
EINECS	Contact for details

Quality Control

Our N2-[(Vinyloxy)Carbonyl]-L-Asparagine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.