Description

Pipotiazine is a high-purity pharmaceutical intermediate and active ingredient belonging to the phenothiazine class of compounds. It is a critical building block in the synthesis of advanced antipsychotic medications, where its structural properties are essential for specific pharmacological activity. This compound is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in the development and production of neuropsychiatric therapeutics. Consistent quality and reliable supply are paramount for ensuring the integrity of downstream pharmaceutical processes.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key active component in the formulation of antipsychotic injectable depot medications.
• Pharmaceutical Intermediate: Serves as a crucial synthetic precursor in multi-step organic synthesis for novel neuroleptic agents.
• Research & Development: Used in preclinical and clinical research studies investigating treatments for schizophrenia and other psychotic disorders.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Process Development: Utilized in scaling up and optimizing synthetic routes for commercial pharmaceutical manufacturing.

Basic Information

Product Name	Pipotiazine
CAS No.	39860-99-6
Molecular Formula	C₂₄H₃₃N₃O₂S₂
Molecular Weight	475.66 g/mol
Synonyms	Piportil; Piportyl; Pipothiazine; 10-[3-(4-(2-Hydroxyethyl)piperazin-1-yl)propyl]-2-(trifluoromethyl)-10H-phenothiazine; 10-[3-[4-(2-Hydroxyethyl)piperazin-1-yl]propyl]-2-(trifluoromethyl)phenothiazine; RP 19366; CL 71563; Pipotiazine Palmitate (ester derivative)
EINECS	Contact for details

Quality Control

Our Pipotiazine is manufactured under strict quality management systems to ensure it meets the exacting standards required for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and GC. We provide full traceability and support regulatory submissions with comprehensive documentation. Certificates of Analysis (COA) detailing all test results are available upon request to ensure compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Follow standard laboratory safety practices for handling fine chemical powders.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.