Description

Methyl 4-(4-Fluorophenyl)-2,4-Dioxobutanoate is a high-purity fluorinated organic building block, specifically a β-keto ester derivative, essential for advanced synthetic chemistry. Its core value lies in its versatile diketone functionality, which serves as a key precursor for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Heterocyclic Chemistry: Serves as a versatile starting material for constructing pyrazoles, isoxazoles, and other nitrogen-containing heterocycles via condensation reactions.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoactive materials due to its conjugated diketone system.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.
• Academic & Institutional Research: Used in university and institutional labs for methodological development and exploring new reaction pathways in fluorine chemistry.

Basic Information

Product Name	Methyl 4-(4-Fluorophenyl)-2,4-Dioxobutanoate
CAS No.	39757-34-1
Molecular Formula	C11H9FO4
Molecular Weight	224.19 g/mol
Synonyms	Methyl 4-(4-fluorophenyl)-2,4-dioxobutanoate; 4-(4-Fluorophenyl)-2,4-dioxobutanoic Acid Methyl Ester; 2,4-Dioxo-4-(4-fluorophenyl)butyric Acid Methyl Ester; Methyl 4-(p-fluorophenyl)-2,4-dioxobutanoate; 4-Fluorophenyl Diketone Ester; 39757-34-1; MFCD03427200
EINECS	Contact for details

Quality Control

Our Methyl 4-(4-Fluorophenyl)-2,4-Dioxobutanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.