Description

Acth (5-24) CAS NO 39603-68-4 is a synthetic peptide fragment corresponding to the 5-24 amino acid sequence of the adrenocorticotropic hormone (ACTH). This compound is a critical research tool for studying the structure-activity relationships of ACTH and its interaction with melanocortin receptors. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on endocrinology, dermatology, and metabolic disorder research.

Application

• Biochemical Research: Used as a reference standard and substrate in studies investigating ACTH receptor binding, signal transduction, and peptide hormone function.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the development of novel therapeutic agents targeting adrenal function and inflammatory pathways.
• Diagnostic Reagent Manufacturing: Employed in the production of immunoassay kits and diagnostic reagents for measuring ACTH levels in clinical samples.
• Academic Studies: Facilitates fundamental research in endocrinology, exploring the role of specific ACTH domains in steroidogenesis and stress response.
• Peptide Chemistry: Acts as a model compound for method development in peptide synthesis, purification, and analytical characterization techniques.

Basic Information

Product Name	Acth (5-24)
CAS No.	39603-68-4
Molecular Formula	C₁₁₂H₁₆₅N₃₁O₃₃S
Molecular Weight	2504.8 g/mol
Synonyms	ACTH (5-24); Adrenocorticotropic Hormone (5-24); Corticotropin (5-24); H-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH; ACTH Fragment 5-24; [5-24]-ACTH; Melanocortin Receptor Ligand Fragment
EINECS	Contact for details

Quality Control

Our Acth (5-24) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade standards. Custom synthesis to meet specific purity requirements (e.g., >95%, >98%) is available.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant use and storage under inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Peptide Content (AAA)	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.