Description

2-[(4-Fluorobenzoyl)Amino]-3-(1H-Indol-3-Yl)Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a fluorinated benzoyl group and an indole moiety, making it a valuable synthetic intermediate. This compound is essential for researchers and manufacturers requiring precise building blocks for complex molecular synthesis. It is primarily utilized in the pharmaceutical and advanced chemical research sectors for developing novel active pharmaceutical ingredients (APIs) and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Peptide Mimetics Research: Used to incorporate fluorinated aromatic and indole characteristics into peptide backbones for structure-activity relationship (SAR) studies.
• Biochemical Probe Development: Acts as a key component in designing fluorescent or affinity tags for studying protein interactions and enzyme functions.
• Organic Synthesis Building Block: Provides a versatile scaffold for medicinal chemists to create libraries of compounds for high-throughput screening.
• Academic & Institutional Research: Employed in university and R&D laboratory settings for fundamental research in bioorganic and medicinal chemistry.

Basic Information

Product Name	2-[(4-Fluorobenzoyl)Amino]-3-(1H-Indol-3-Yl)Propanoic Acid
CAS No.	39545-02-3
Molecular Formula	C18H15FN2O3
Molecular Weight	326.32 g/mol
Synonyms	N-(4-Fluorobenzoyl)-L-tryptophan; 4-Fluoro-N-[(2S)-1-hydroxy-3-(1H-indol-3-yl)-1-oxopropan-2-yl]benzamide; 2-[(4-Fluorobenzoyl)amino]-3-(1H-indol-3-yl)propanoic acid; (S)-2-((4-Fluorobenzamido)-3-(1H-indol-3-yl)propanoic acid; N4-Fluorobenzoyl-L-tryptophan; L-Tryptophan, N-(4-fluorobenzoyl)-; Fmoc-L-Trp(4-F-Bz)-OH (precursor form); 4-F-Bz-L-Trp-OH
EINECS	Contact for details

Quality Control

Our 2-[(4-Fluorobenzoyl)Amino]-3-(1H-Indol-3-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.