Description

Staphylococcal Enterotoxin B (SEB) is a potent exotoxin produced by *Staphylococcus aureus* and is a key superantigen that triggers a massive immune response. This product is essential for research and development in immunology, toxicology, and biodefense, providing a critical reference standard for assay development and validation. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and diagnostic kit manufacturers focused on pathogen detection and immune system studies.

Application

• Immunological Research: Used as a model superantigen to study T-cell activation, cytokine storms, and immune system modulation.
• Diagnostic Development: Serves as a critical antigen and positive control in the development of immunoassays (ELISA, lateral flow) for detecting Staphylococcal enterotoxins in food, clinical, and environmental samples.
• Toxicology Studies: Employed in research to understand the mechanisms of toxin-induced shock, organ failure, and to evaluate potential therapeutic countermeasures.
• Vaccine and Antitoxin Research: Acts as a key antigen for the development and potency testing of vaccines and neutralizing antibodies against SEB.
• Quality Control & Standardization: Used as a certified reference material (CRM) to calibrate equipment and validate analytical methods in quality control laboratories.
• Biodefense and Biosafety Research: Utilized in secure facilities for studies related to pathogenicity, detection, and decontamination protocols for potential biological threats.

Basic Information

Product Name	Enterotoxin B, Staphylococcal
CAS No.	39424-53-8
Molecular Formula	Contact for details
Molecular Weight	~28.4 kDa (Monomer)
Synonyms	SEB; Staphylococcal Enterotoxin B; *Staphylococcus aureus* Enterotoxin B; SEA; Enterotoxin Type B; Superantigen SEB; SEB Toxin
EINECS	Contact for details

Quality Control

Our Staphylococcal Enterotoxin B is produced and handled under stringent conditions to ensure high purity and biological activity. Each batch is subjected to rigorous analytical testing, including purity assessment, identity confirmation, and endotoxin level checks. A comprehensive Certificate of Analysis (COA) detailing purity, potency (where applicable), and analytical methods is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated. Aliquot into working solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/Immunoassay)	Conforms to Standard
Purity (SDS-PAGE / HPLC)	≥ 95%
Protein Content (BCA/Bradford)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (in vitro assay)	Contact for details
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.