Description

Botropase CAS NO 39423-21-7 is a highly purified, standardized enzyme preparation derived from snake venom, primarily used as a hemostatic agent. It is a critical component in pharmaceutical formulations designed to control bleeding during surgical procedures and in the management of hemorrhagic disorders. This product is essential for manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing and producing hemostatic drugs, topical ointments, and diagnostic reagents for coagulation studies.

Application

• Pharmaceutical Hemostats: Active pharmaceutical ingredient (API) in topical and injectable formulations to control capillary bleeding in surgical and dental procedures.
• Coagulation Research: Essential reagent in biochemical and pharmacological research for studying blood coagulation pathways, platelet aggregation, and fibrinolysis.
• Diagnostic Kits: Key component in in-vitro diagnostic (IVD) kits for assessing clotting time and other hemostatic parameters in clinical laboratories.
• Biotechnology: Used as a proteolytic enzyme in specific bioprocessing applications and for the study of enzyme kinetics and inhibition.
• Veterinary Medicine: Incorporated into hemostatic products for controlling bleeding in veterinary surgery and trauma care.

Basic Information

Product Name	Botropase
CAS No.	39423-21-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Batroxobin; Reptilase; Defibrase; Botropase; Bothrops atrox Venom Enzyme; Coagulating Enzyme; Venzyme; Hemocoagulase
EINECS	Contact for details

Quality Control

Our Botropase is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, meeting the stringent requirements for pharmaceutical-grade enzymes. Certificates of Analysis (COA) detailing specifications for activity (NIH units/mg), protein content, and purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms
Assay (Activity)	≥ 1000 NIH units/mg protein
Protein Content (Biuret)	≥ 90%
Purity (SDS-PAGE)	Single band
pH (1% Solution)	6.0 - 7.5
Loss on Drying	≤ 5.0%
Bacterial Endotoxins (LAL)	< 10 EU/mg
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.