Description

(3S,αr)-3-[[[4-[(R)-3-Amino-3-Carboxypropoxy]Phenyl]-[(Z)-Hydroxyimino]Acetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid is a sophisticated, high-purity β-lactam derivative of significant interest in advanced pharmaceutical synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the discovery and production of next-generation antibiotics and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel β-lactam antibiotics.
• API Synthesis: Used as a building block in the multi-step synthesis of complex target molecules for clinical candidates.
• Medicinal Chemistry Research: Valuable for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Bioconjugation: Potential use in creating targeted drug conjugates due to its reactive functional groups.
• Chemical Biology Probes: Can be utilized in the development of probes for studying bacterial enzyme mechanisms.

Basic Information

Product Name	(3S,αr)-3-[[[4-[(R)-3-Amino-3-Carboxypropoxy]Phenyl]-[(Z)-Hydroxyimino]Acetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid
CAS No.	39391-39-4
Molecular Formula	C23H24N4O9
Molecular Weight	500.46 g/mol
Synonyms	3-[[[4-[(R)-3-Amino-3-Carboxypropoxy]Phenyl]-[(Z)-Hydroxyimino]Acetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid, (3S,αr)-Isomer; (3S,alphaR)-3-[[4-[(R)-3-Amino-3-carboxypropoxy]phenylacetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid; 39391-39-4; β-Lactam derivative intermediate; Azetidineacetic acid derivative
EINECS	Contact for details

Quality Control

Our (3S,αr)-3-[[[4-[(R)-3-Amino-3-Carboxypropoxy]Phenyl]-[(Z)-Hydroxyimino]Acetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.