Description

2-Chloroadenosine-3',5'-Cyclic Monophosphate Sodium Salt is a chemically modified, cell-permeable analog of cyclic adenosine monophosphate (cAMP), a fundamental secondary messenger in cellular signaling pathways. This compound is valued for its enhanced stability and potent activity as a protein kinase A (PKA) activator, making it a critical tool for modulating intracellular signaling in research. It is primarily utilized by pharmaceutical researchers, biochemical laboratories, and academic institutions investigating signal transduction, cardiac function, and metabolic regulation.

Application

• Biochemical Research: A key tool for studying cAMP-dependent protein kinase (PKA) signaling pathways and their role in cellular processes.
• Pharmaceutical Development: Used in preclinical studies to investigate potential therapeutic targets for cardiac diseases, metabolic disorders, and neurological conditions.
• Cell Biology Studies: Employed to modulate intracellular cAMP levels to examine effects on gene expression, ion channel activity, and cell differentiation.
• Enzyme Activation Studies: Serves as a stable agonist for PKA activation in in vitro assay systems.
• Metabolic Research: Applied in studies exploring the regulation of glycogen, lipid, and steroid metabolism.
• Signal Transduction Probes: Used as a molecular probe to dissect complex signaling networks and cross-talk between pathways.

Basic Information

Product Name	2-Chloroadenosine-3',5'-Cyclic Monophosphate Sodium Salt
CAS No.	39023-65-9
Molecular Formula	C10H10ClN5NaO6P
Molecular Weight	409.64 g/mol
Synonyms	2-Cl-cAMP Sodium Salt; 2-Chloro-cyclic AMP Sodium Salt; 2-Chloroadenosine cyclic 3',5'-(hydrogen phosphate) sodium salt; 2-Chloro-3',5'-cyclic adenosine monophosphate sodium salt; 2-Chloro-cyclic adenosine monophosphate sodium salt; Sodium 2-chloroadenosine-3',5'-cyclic monophosphate; 2-Cl-Ado-3',5'-cMP Na salt
EINECS	Contact for details

Quality Control

Our 2-Chloroadenosine-3',5'-Cyclic Monophosphate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.