Description

4-Trifluoromethyl-Benzamidine Hcl is a high-purity organic building block featuring a benzamidine core functionalized with a trifluoromethyl group. This compound is valued for its role as a key synthetic intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily sought after by research institutions and industrial manufacturers engaged in medicinal chemistry, particularly for the synthesis of protease inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially protease inhibitors and enzyme modulators.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the amidine and trifluoromethyl groups.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex heterocyclic compounds and fine chemicals.
• Biochemical Tool Compound: Employed in biochemical assays and as a research probe to study enzyme mechanisms and binding interactions.
• Material Science Research: Investigated for potential use in the synthesis of specialty polymers and advanced functional materials.

Basic Information

Product Name	4-Trifluoromethyl-Benzamidine Hcl
CAS No.	38980-96-0
Molecular Formula	C8H8ClF3N2
Molecular Weight	224.61 g/mol
Synonyms	4-(Trifluoromethyl)benzamidine hydrochloride; Benzenecarboximidamide, 4-(trifluoromethyl)-, hydrochloride (1:1); p-Trifluoromethylbenzamidine HCl; 4-Carbamimidoylbenzotrifluoride hydrochloride; α,α,α-Trifluoro-p-toluamidine hydrochloride; 4-(Trifluoromethyl)benzenecarboximidamide monohydrochloride
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethyl-Benzamidine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.