Description

Z-Ile-Leu-Oh CAS NO 38972-95-1 is a protected dipeptide derivative, specifically the C-terminal carboxylic acid of the Z-protected Ile-Leu sequence. This compound serves as a crucial building block in solid-phase and solution-phase peptide synthesis, enabling the controlled elongation of peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for developing novel therapeutic peptides and biochemical probes.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of longer, biologically active peptide sequences for drug discovery and development.
• Biochemical Research: Used as a standard or reagent in proteomics research, enzyme substrate studies, and metabolic pathway analysis.
• Peptide Library Construction: Essential component in the combinatorial synthesis of peptide libraries for high-throughput screening against various biological targets.
• Custom Peptide Synthesis: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom peptides for clients.
• Prodrug Development: Potential use in designing peptide-based prodrugs where specific dipeptide sequences are used for targeted drug delivery.

Basic Information

Product Name	Z-Ile-Leu-Oh
CAS No.	38972-95-1
Molecular Formula	C₂₁H₃₂N₂O₅
Molecular Weight	392.49 g/mol
Synonyms	N-Benzyloxycarbonyl-L-isoleucyl-L-leucine; Z-Ile-Leu-OH; Z-L-Ile-L-Leu-OH; Cbz-Ile-Leu-OH; N-Cbz-L-isoleucyl-L-leucine; Benzyloxycarbonylisoleucylleucine; (2S)-2-[[(2S)-2-[[(phenylmethoxy)carbonyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
EINECS	Contact for details

Quality Control

Our Z-Ile-Leu-Oh is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure stereochemical integrity. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support GMP-grade applications for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.