Description

Aristolochic Acid-Ia CAS NO 38965-71-8 is a specific, naturally occurring nitrophenanthrene carboxylic acid derivative, recognized for its distinct chemical structure and biological activity. This compound is of significant interest in biochemical and pharmacological research, serving as a critical reference standard and investigative tool. It is primarily utilized by research institutions, pharmaceutical development laboratories, and analytical service providers engaged in toxicology, phytochemistry, and metabolic pathway studies.

Application

• Phytochemical Reference Standard: Used for the qualitative and quantitative analysis of plant extracts and traditional herbal preparations.
• Toxicological Research: Serves as a key analyte in studies investigating nephrotoxicity and carcinogenicity associated with Aristolochia species.
• Biochemical Pathway Analysis: Employed in research to understand the metabolic activation, DNA adduct formation, and detoxification pathways of aristolochic acids.
• Analytical Method Development: Essential for developing and validating sensitive HPLC, LC-MS, or GC-MS methods for the detection of aristolochic acids in complex matrices.
• Quality Control in Herbal Medicine: Acts as a marker compound for the screening and prohibition of Aristolochia-containing ingredients in regulated products to ensure consumer safety.
• Academic and Pharmaceutical Research: Used in fundamental research exploring structure-activity relationships and the mechanisms of action of nitrophenanthrene compounds.

Basic Information

Product Name	Aristolochic Acid-Ia
CAS No.	38965-71-8
Molecular Formula	C17H11NO7
Molecular Weight	341.27 g/mol
Synonyms	Aristolochic Acid A; 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic Acid; Aristolochic Acid I; Aristolochic acid; Isoaristolochic acid; Tardolyt; Aristolochin
EINECS	Contact for details

Quality Control

Our Aristolochic Acid-Ia is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant standards for high-purity biochemical reagents, ensuring the material is suitable for use as an analytical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider conditions as recommended on the specific product label or COA.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder or crystals
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical grades: 95%, 98%, 99%)
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.