Description

Sodium [6R-[6Alpha,7Beta(R*)]]-7-(Aminophenylacetamido)-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate is the sodium salt of a key intermediate in the synthesis of advanced cephalosporin antibiotics. This high-purity compound is critical for ensuring the efficacy and safety of the final active pharmaceutical ingredient (API). It is an essential building block for pharmaceutical manufacturers and research institutions developing next-generation antibacterial agents to combat resistant infections.

Application

• Pharmaceutical Intermediate: Primary use as a critical synthetic precursor in the manufacture of cephalosporin-class antibiotics.
• API Synthesis: Serves as a key building block for the production of active pharmaceutical ingredients (APIs) targeting a broad spectrum of bacterial infections.
• Antibacterial Research: Used in R&D laboratories for the development and study of new β-lactam antibiotic compounds and their structure-activity relationships.
• Process Chemistry: Employed in scaling up and optimizing synthetic routes for antibiotic production under current Good Manufacturing Practices (cGMP).
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and regulatory testing of cephalosporin drugs.

Basic Information

Product Name	Sodium [6R-[6Alpha,7Beta(R*)]]-7-(Aminophenylacetamido)-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
CAS No.	38932-40-0
Molecular Formula	C16H16N3NaO5S
Molecular Weight	385.37 g/mol
Synonyms	Sodium 7-ADCA derivative; Sodium (6R,7R)-7-Amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7-(Phenylglycyl) derivative; Cephalosporin C sodium salt intermediate; 7-ADCA phenylglycyl sodium salt; 7-ACA derivative sodium salt; Sodium 3-methyl-7-(2-phenyl-2-aminoacetamido)ceph-3-em-4-carboxylate; Sodium 7-[(Aminophenylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade intermediate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and related substances, to ensure it meets the stringent requirements for API synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.