Description

4-[3,5-Bis(Trifluoromethyl)Phenyl]-3-Thiosemicarbazide is a specialized organic compound featuring a thiosemicarbazide core flanked by a highly fluorinated aromatic ring. This structure imparts unique chemical properties, making it a valuable intermediate for the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting specific enzyme inhibition.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl groups enhance biological activity and stability.
• Material Science Research: Serves as a precursor for ligands or monomers in the development of specialty polymers and advanced materials with specific electronic or surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Catalyst and Ligand Development: Acts as a starting material for synthesizing novel chelating agents or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	4-[3,5-Bis(Trifluoromethyl)Phenyl]-3-Thiosemicarbazide
CAS No.	38901-31-4
Molecular Formula	C9H5F6N3S
Molecular Weight	293.21 g/mol
Synonyms	1-[3,5-Bis(trifluoromethyl)phenyl]-3-thiosemicarbazide; 3,5-Bis(trifluoromethyl)phenyl thiosemicarbazide; 4-[3,5-Bis(trifluoromethyl)phenyl]thiosemicarbazide; 1-(3,5-Bis(trifluoromethyl)phenyl)-2-thiosemicarbazide; 3-Thiosemicarbazido-3',5'-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)benzenecarbothiohydrazide; 38901-31-4; AKOS BRN-0767
EINECS	Contact for details

Quality Control

Our 4-[3,5-Bis(Trifluoromethyl)Phenyl]-3-Thiosemicarbazide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.