Description

4-[2-(Trifluoromethyl)Phenyl]-3-Thiosemicarbazide is a specialized organic intermediate featuring a trifluoromethylphenyl group linked to a thiosemicarbazide moiety. This compound matters for its role as a critical building block in the synthesis of advanced heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer, leveraging the thiosemicarbazide pharmacophore.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and stability.
• Coordination Chemistry: Serves as a versatile ligand for metal complexation, useful in creating catalysts or materials with specific magnetic or optical properties.
• Heterocyclic Synthesis: Fundamental building block for constructing nitrogen and sulfur-containing heterocycles like thiadiazoles and triazoles.
• Chemical Biology Probes: Employed in research to develop molecular probes for studying enzyme inhibition or cellular processes.

Basic Information

Product Name	4-[2-(Trifluoromethyl)Phenyl]-3-Thiosemicarbazide
CAS No.	38901-29-0
Molecular Formula	C8H8F3N3S
Molecular Weight	235.23 g/mol
Synonyms	1-[2-(Trifluoromethyl)phenyl]-3-thiosemicarbazide; 2-(Trifluoromethyl)phenyl thiosemicarbazide; 3-Thiosemicarbazido-2'-trifluoromethylbenzene; 4-[2-(Trifluoromethyl)phenyl]-3-thiosemicarbazide; α,α,α-Trifluoro-o-tolyl thiosemicarbazide; N-(2-Trifluoromethylphenyl)hydrazinecarbothioamide
EINECS	Contact for details

Quality Control

Our 4-[2-(Trifluoromethyl)Phenyl]-3-Thiosemicarbazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from techniques including HPLC, NMR, and IR spectroscopy. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.