Description

(R)-1-Benzyl-5-Carboxy-2-Pyrrolidinone is a high-value, chiral pyrrolidinone derivative that serves as a critical building block in advanced organic synthesis. Its significance lies in its role as a key intermediate for the production of complex pharmaceutical compounds, particularly those requiring specific stereochemistry. This product is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries who are developing active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, especially for neurological and cardiovascular targets.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to construct stereogenic centers.
• Peptidomimetic Research: Serves as a constrained scaffold or proline analogue in the design of novel peptide-based therapeutics.
• API Development: Critical for the research, development, and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals and complex organic molecules.
• Academic & Industrial R&D: A valuable reagent for methodological development and discovery chemistry in laboratory settings.

Basic Information

Product Name	(R)-1-Benzyl-5-Carboxy-2-Pyrrolidinone
CAS No.	38854-94-3
Molecular Formula	C13H15NO3
Molecular Weight	233.26 g/mol
Synonyms	(R)-1-Benzyl-5-carboxypyrrolidin-2-one; (R)-1-Benzyl-2-oxopyrrolidine-5-carboxylic Acid; (5R)-1-Benzyl-5-carboxy-2-pyrrolidinone; (R)-N-Benzyl-5-carboxy-2-pyrrolidinone; (R)-α-Benzyl-α-carboxy-γ-butyrolactam; (R)-1-Benzyl-5-carboxy-2-oxopyrrolidine; (R)-N-Benzyl-2-oxo-5-pyrrolidinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our (R)-1-Benzyl-5-Carboxy-2-Pyrrolidinone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP standards where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.