Description

n-Octanoylnornicotine is a chemically modified nicotine derivative, specifically an N-acylnornicotine, where an octanoyl group is attached to the nornicotine base. This compound is of significant interest in advanced research and development, particularly for its potential as a synthetic intermediate or a reference standard in analytical chemistry. It serves specialized roles in the pharmaceutical and life science sectors, where precise molecular structures are required for metabolic studies, receptor binding assays, and the development of novel nicotine-related compounds. Researchers and developers in medicinal chemistry and analytical laboratories are the primary users of this high-purity specialty chemical.

Application

• Pharmaceutical Research Intermediate: Used in the synthesis and development of novel nicotine analogs and receptor-targeted compounds for therapeutic research.
• Analytical Reference Standard: Serves as a high-purity certified standard for quality control and method validation in HPLC, LC-MS, and GC-MS analysis within analytical laboratories.
• Metabolic and Pharmacokinetic Studies: Employed as a probe or metabolite analog in studies investigating the absorption, distribution, metabolism, and excretion (ADME) of nicotine derivatives.
• Neuroscience and Receptor Binding Assays: Utilized in biochemical research to study interactions with nicotinic acetylcholine receptors (nAChRs) and related neurological pathways.
• Chemical Synthesis Building Block: Acts as a key precursor for the preparation of more complex, functionalized molecules in medicinal and synthetic organic chemistry.

Basic Information

Product Name	n-Octanoylnornicotine
CAS No.	38854-10-3
Molecular Formula	C₁₈H₂₈N₂O
Molecular Weight	288.43 g/mol
Synonyms	Octanoylnornicotine; N-Octanoylnornicotine; 1-(3-(1-Methylpyrrolidin-2-yl)pyridin-5-yl)octan-1-one; 5-(1-Oxooctyl)-3-(1-methyl-2-pyrrolidinyl)pyridine; Nornicotine n-octanoate; 38854-10-3; 1-Octanoyl-nornicotine
EINECS	Contact for details

Quality Control

Every batch of n-Octanoylnornicotine is manufactured and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure compliance with exacting research-grade standards. A comprehensive Certificate of Analysis (COA), detailing batch-specific results, is provided with each shipment to guarantee traceability and support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.