Description

Cefradine CAS NO 38821-53-3 is a first-generation cephalosporin antibiotic belonging to the β-lactam class. This semi-synthetic compound is valued for its broad-spectrum bactericidal activity against a wide range of Gram-positive and some Gram-negative bacteria. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the production of oral and injectable antibiotic formulations. Its efficacy and established safety profile make it a cornerstone in treating various bacterial infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of oral capsules, tablets, and injectable antibiotic preparations.
• Human Medicine: Formulated for treating respiratory tract infections, skin and soft tissue infections, urinary tract infections, and other susceptible bacterial diseases.
• Veterinary Medicine: Used in veterinary pharmaceuticals for treating bacterial infections in livestock and companion animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for studying antibiotic efficacy and resistance.
• Generic Drug Production: A vital component for manufacturers producing generic cephalosporin medications for global markets.

Basic Information

Product Name	Cefradine
CAS No.	38821-53-3
Molecular Formula	C16H19N3O4S
Molecular Weight	349.41 g/mol
Synonyms	Cephradine; Cefradinum; Cephradinum; (±)-Cefradine; 7-[(2R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Anspor; Velosef; Sefril
EINECS	254-110-6

Quality Control

Our Cefradine is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP, EP, and BP. Every batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis to ensure high purity and consistent potency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 6.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
pH (1% aqueous solution)	3.5 - 6.0
Specific Optical Rotation	+80° to +90°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.