Description

trans-1-Iodo-2-(Pentafluoroethyl)Cyclohexane is a high-value, halogenated organic building block characterized by its unique cyclohexane backbone functionalized with iodine and a pentafluoroethyl group. This compound is essential for introducing fluorinated motifs and iodine handles into complex molecular architectures, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for applications in cross-coupling reactions and as a precursor for novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of fluorinated drug candidates, particularly for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated organic semiconductors and liquid crystal compounds, improving electronic properties and thermal stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, imparting valuable properties like oil/water repellency and chemical resistance.
• Radiolabeling Precursor: The iodine moiety provides a potential site for radioiodination, useful in developing diagnostic imaging agents.
• Organic Synthesis Reagent: A versatile reagent for constructing complex, fluorinated organic molecules in academic and industrial research settings.

Basic Information

Product Name	trans-1-Iodo-2-(Pentafluoroethyl)Cyclohexane
CAS No.	38787-67-6
Molecular Formula	C8H10F5I
Molecular Weight	328.06 g/mol
Synonyms	trans-1-Iodo-2-(pentafluoroethyl)cyclohexane; 1-Iodo-2-(pentafluoroethyl)cyclohexane (trans-); 2-(Pentafluoroethyl)-1-iodocyclohexane; (1R,2R)-1-Iodo-2-(pentafluoroethyl)cyclohexane; (1S,2S)-1-Iodo-2-(pentafluoroethyl)cyclohexane; trans-2-(Pentafluoroethyl)-1-iodocyclohexane; Cyclohexane, 1-iodo-2-(pentafluoroethyl)-, trans-
EINECS	Contact for details

Quality Control

Our trans-1-Iodo-2-(Pentafluoroethyl)Cyclohexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its light-sensitive nature and organic solvent compatibility, handle and store under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (GC/HPLC)	≥ 95.0% trans-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.