Description

2-Bromo-4-Ethylbenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a nitrile group on an ethylbenzene core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as a precursor to various functional groups.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating molecules with specific aromatic substitution patterns.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the bromine atom facilitates further functionalization.
• Material Science Research: Acts as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Synthesis: Utilized in academic and industrial R&D laboratories for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-4-Ethylbenzonitrile
CAS No.	38678-87-4
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	4-Ethyl-2-bromobenzonitrile; 2-Bromo-4-ethylbenzonitrile; Benzonitrile, 2-bromo-4-ethyl-; 2-Bromo-4-ethyl-benzonitrile; (2-Bromo-4-ethylphenyl)carbonitrile; 38678-87-4 (CAS); 2-Br-4-Et-Ph-CN
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Ethylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.