Description

2-Amino-4-Chlorobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a nitrile group on a chlorinated benzene ring, makes it a valuable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it enables the development of novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides, leveraging its chloroaniline and benzonitrile functionalities.
• Dye and Pigment Manufacturing: Used in the production of azo dyes and other complex colorants for textiles and industrial applications.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for electron-transport materials and other functional layers in electronic displays.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis in fine chemical production.
• Polymer Modification: Acts as a monomer or cross-linking agent for engineering high-performance polymers with specific thermal or chemical resistance.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-Amino-4-Chlorobenzonitrile
CAS No.	38487-86-4
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	4-Chloro-2-aminobenzonitrile; 2-Amino-4-chlorobenzene carbonitrile; 4-Chloroanthranilonitrile; 2-Cyano-5-chloroaniline; 5-Chloro-2-aminobenzonitrile; 4-Chloro-2-cyanobenzenamine; Benzonitrile, 2-amino-4-chloro-
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Chlorobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material is suitable for demanding pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be opaque or kept in dark conditions. Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.