Description

4-Methoxy-2-Nitrobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring both electron-donating methoxy and electron-withdrawing nitro and nitrile groups, makes it a valuable building block for constructing complex heterocyclic systems and functional materials. This high-purity compound is essential for research and development laboratories, pharmaceutical manufacturers, and agrochemical producers seeking to develop new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators due to its bioactive nitroaromatic core.
• Dye and Pigment Manufacturing: Intermediate in the production of advanced colorants, optical brighteners, and specialty dyes for textiles and polymers.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and non-linear optical (NLO) materials.
• Chemical Research & Development: Versatile scaffold for medicinal chemistry, combinatorial library synthesis, and structure-activity relationship (SAR) studies.
• Complex Ligand Synthesis: Starting material for creating specialized ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	4-Methoxy-2-Nitrobenzonitrile
CAS No.	38469-83-9
Molecular Formula	C8H6N2O3
Molecular Weight	178.15 g/mol
Synonyms	2-Nitro-4-methoxybenzonitrile; 4-Methoxy-2-nitrobenzenecarbonitrile; Benzonitrile, 4-methoxy-2-nitro-; 4-Methoxy-2-nitro-benzonitrile; p-Methoxy-o-nitrobenzonitrile; 2-Cyano-5-nitroanisole; 4-Methoxy-2-nitro-phenyl cyanide; NSC 403119
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxy-2-Nitrobenzonitrile is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure consistency and purity. Our products are suitable for demanding R&D and scale-up applications, with specifications typically meeting or exceeding 98% purity (HPLC). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, assay, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from direct light exposure. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.