Description

4α,5α-Diisopropyl-2,2-Bis(Trifluoromethyl)-1,3-Dioxolane is a specialized fluorinated dioxolane derivative, a high-value intermediate prized for its unique steric and electronic properties imparted by the trifluoromethyl groups. This compound matters for its role in advanced synthesis, particularly in the development of pharmaceuticals and agrochemicals where fluorine incorporation is critical for enhancing metabolic stability, bioavailability, and lipophilicity. It is essential for R&D chemists and process development scientists in fine chemical, pharmaceutical, and agrochemical industries seeking to introduce robust, fluorinated protecting groups or building blocks into complex molecular architectures.

Application

• As a fluorinated protecting group reagent for sensitive carbonyl functionalities in multi-step organic synthesis.
• As a key building block (synthon) for the preparation of complex fluorinated molecules in pharmaceutical research.
• In the synthesis of agrochemical active ingredients, where fluorination improves pesticidal activity and environmental persistence.
• For the development of advanced materials, such as fluorinated polymers or liquid crystals with specific dielectric properties.
• In catalysis research as a ligand precursor or to modify catalyst solubility and reactivity.
• As a standard or reference compound in analytical chemistry for method development in GC-MS or LC-MS.

Basic Information

Product Name	4α,5α-Diisopropyl-2,2-Bis(Trifluoromethyl)-1,3-Dioxolane
CAS No.	38363-92-7
Molecular Formula	C11H16F6O2
Molecular Weight	294.24 g/mol
Synonyms	4,5-Diisopropyl-2,2-bis(trifluoromethyl)-1,3-dioxolane; 2,2-Bis(trifluoromethyl)-4,5-diisopropyl-1,3-dioxolane; 4α,5α-Diisopropyl-2,2-bis(trifluoromethyl)-1,3-dioxolane; Dioxolane, 4,5-diisopropyl-2,2-bis(trifluoromethyl)-; Fluorinated dioxolane derivative; DIPBTF-Dioxolane
EINECS	Contact for details

Quality Control

Our 4α,5α-Diisopropyl-2,2-Bis(Trifluoromethyl)-1,3-Dioxolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.