Description

Rel-(4R*,5R*)-2,2-Bis(Trifluoromethyl)-4-Ethyl-5-Hexyl-1,3-Dioxolane is a specialized fluorinated dioxolane derivative characterized by its unique stereochemistry and trifluoromethyl groups. This compound matters for its role as a high-performance intermediate and solvent in advanced chemical synthesis, offering enhanced stability and specific reactivity profiles. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for developing novel fluorinated compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the metabolic stability imparted by the CF3 groups.
• Agrochemical Synthesis: Serves as a key building block for creating novel herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Specialty Solvent: Acts as a high-performance, non-protic solvent for reactions requiring anhydrous conditions and compatibility with strong acids or organometallic reagents.
• Ligand & Catalyst Development: Employed in the design of chiral ligands and catalysts for asymmetric synthesis, benefiting from its defined stereocenters.
• Fluoropolymer & Material Science: Used as a monomer or modifier in the development of advanced fluoropolymers and specialty materials with unique surface properties.
• Electrolyte Additive: Investigated for use as a stabilizing additive in lithium-ion battery electrolytes to enhance performance and safety.

Basic Information

Product Name	Rel-(4R*,5R*)-2,2-Bis(Trifluoromethyl)-4-Ethyl-5-Hexyl-1,3-Dioxolane
CAS No.	38274-67-8
Molecular Formula	C13H20F6O2
Molecular Weight	322.29 g/mol
Synonyms	4-Ethyl-5-hexyl-2,2-bis(trifluoromethyl)-1,3-dioxolane (rel-(4R,5R)-form); 1,3-Dioxolane, 2,2-bis(trifluoromethyl)-4-ethyl-5-hexyl-, rel-(4R,5R)-; 2,2-Bis(trifluoromethyl)-4-ethyl-5-hexyl-1,3-dioxolane; Fluorinated Dioxolane Derivative; (rel)-(4R,5R)-4-Ethyl-5-hexyl-2,2-bis(trifluoromethyl)-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our Rel-(4R*,5R*)-2,2-Bis(Trifluoromethyl)-4-Ethyl-5-Hexyl-1,3-Dioxolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids and bases. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.