Description

34-Methylcyanocobalamin is a synthetic, organometallic form of vitamin B12, distinguished by its methyl group substitution at the 34-position. This compound is valued for its high purity and stability, making it a critical reference standard and active ingredient in advanced pharmaceutical and research applications. It is essential for manufacturers and research institutions requiring a precisely characterized form of cobalamin for analytical, diagnostic, and high-grade nutraceutical development.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and assay validation of vitamin B12 products in pharmacopoeial testing (USP, EP).
• Active Pharmaceutical Ingredient (API): Serves as a key component in the formulation of high-potency vitamin B12 supplements and prescription medications.
• Biochemical Research: Employed in enzymatic studies, metabolic pathway analysis, and as a cofactor in research involving methyltransferase enzymes.
• Diagnostic Reagent Manufacturing: Utilized in the production of immunoassay kits and other in-vitro diagnostic (IVD) reagents for accurate vitamin B12 level detection.
• Cell Culture & Microbiology: Acts as a growth factor in specialized cell culture media and for the cultivation of certain microorganisms.
• Nutraceutical Formulation: Incorporated into premium-grade dietary supplements targeting specific bioavailability and metabolic support.

Basic Information

Product Name	34-Methylcyanocobalamin
CAS No.	38218-51-8
Molecular Formula	C₆₃H₉₁CoN₁₃O₁₄P
Molecular Weight	1344.40 g/mol
Synonyms	Methylcobalamin (common name); Vitamin B12a methyl derivative; Coα-[α-(5,6-Dimethylbenzimidazolyl)]-Coβ-methylcobamide cyanide; Methylcyanocob(III)alamin; 34-Me-CNCbl; Methyl-B12; Cyanomethylcobalamin; Cobamamide derivative
EINECS	Contact for details

Quality Control

Our 34-Methylcyanocobalamin is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical and research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	Dark red crystalline powder or crystals
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.