Description

7'-Trifluoromethyldihydrocinchonidine is a high-purity, advanced pharmaceutical intermediate and chiral ligand derived from the cinchona alkaloid family. This compound matters for its critical role in asymmetric synthesis, where it acts as a highly selective catalyst or resolving agent to produce enantiomerically pure compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and specialty chemicals.

Application

• As a chiral ligand or catalyst in asymmetric hydrogenation and other transition metal-catalyzed reactions.
• As a key resolving agent for the separation of enantiomers in pharmaceutical development.
• In the research and synthesis of novel active pharmaceutical ingredients (APIs) requiring high stereochemical purity.
• For the development of advanced agrochemicals and specialty fine chemicals.
• As a reference standard in analytical method development and quality control laboratories.
• In academic and industrial research focused on organocatalysis and green chemistry methodologies.

Basic Information

Product Name	7'-Trifluoromethyldihydrocinchonidine
CAS No.	38199-17-6
Molecular Formula	C₂₁H₂₅F₃N₂O
Molecular Weight	378.43 g/mol
Synonyms	7'-Trifluoromethyldihydrocinchonidine; (8S,9R)-7'-Trifluoromethyldihydrocinchonidine; Cinchonidine, 7'-(trifluoromethyl)dihydro-; Dihydro-7'-trifluoromethylcinchonidine; 7'-Trifluoromethyl-10,11-dihydrocinchonidine; (8α,9R)-7'-(Trifluoromethyl)-10,11-dihydrocinchonidine
EINECS	Contact for details

Quality Control

Our 7'-Trifluoromethyldihydrocinchonidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assays, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.