Description

H-Gly-Otbu Acoh CAS NO 38024-18-9 is a protected amino acid derivative, specifically the tert-butyl ester of glycine, commonly used as a crucial building block in organic synthesis. This compound is essential for the controlled formation of peptide bonds, enabling the production of complex molecules with high precision and purity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for applications in drug discovery, peptide synthesis, and the development of novel bioactive compounds.

Application

• Peptide Synthesis: A fundamental building block (glycine derivative) in solid-phase and solution-phase peptide synthesis for constructing peptide chains.
• Pharmaceutical Intermediates: Serves as a key intermediate in the research and production of active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Used in the modification of proteins, antibodies, and other biomolecules for therapeutic and diagnostic applications.
• Protecting Group Strategy: The tert-butyl ester (OtBu) group provides temporary protection for the carboxylic acid functionality during multi-step synthetic sequences.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery.
• Agrochemical Research: Acts as a synthetic precursor in the development of novel pesticides and herbicides.

Basic Information

Product Name	H-Gly-Otbu Acoh
CAS No.	38024-18-9
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	Glycine tert-butyl ester; tert-Butyl glycinate; 2-Aminoacetic acid tert-butyl ester; H-Gly-OtBu; Gly-OtBu; Boc-Gly-OH tert-butyl ester precursor; Glycine, 1,1-dimethylethyl ester; Aminoacetic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our H-Gly-Otbu Acoh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.