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3-[[n-(3-Ethoxy-2,4,6-Triiodophenyl)-n-Ethylamino]Carbonyl]Propionic Acid CAS NO 37938-74-2


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CAS No.:37938-74-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-[[n-(3-Ethoxy-2,4,6-Triiodophenyl)-n-Ethylamino]Carbonyl]Propionic Acid is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. This high-purity intermediate is critical for ensuring the final pharmaceutical product's safety, efficacy, and regulatory compliance. It is essential for manufacturers in the pharmaceutical and diagnostic imaging industries developing non-ionic, low-osmolar contrast agents.

Application

  • Pharmaceutical Intermediate: A crucial building block in the synthesis of modern, non-ionic X-ray contrast agents like iopromide and ioversol.
  • Diagnostic Imaging: Contributes to the production of contrast media used in computed tomography (CT), angiography, and urography.
  • Research & Development: Serves as a reference standard and starting material in medicinal chemistry research for novel iodinated compounds.
  • Fine Chemical Synthesis: Used in advanced organic synthesis to introduce the triiodophenyl moiety into complex molecules.

Basic Information

Product Name 3-[[n-(3-Ethoxy-2,4,6-Triiodophenyl)-n-Ethylamino]Carbonyl]Propionic Acid
CAS No. 37938-74-2
Molecular Formula C14H17I3NO4
Molecular Weight 661.00 g/mol
Synonyms 3-[[N-(3-Ethoxy-2,4,6-triiodophenyl)-N-ethylcarbamoyl]]propanoic Acid; 3-[(N-Ethyl-3-ethoxy-2,4,6-triiodoanilino)carbonyl]propionic Acid; Iopromide Intermediate; Ioversol Intermediate; 2,4,6-Triiodo-3-ethoxy-N-ethyl-N-(3-carboxypropionyl)aniline; 37938-74-2; 3-Carboxypropionyl(3-ethoxy-2,4,6-triiodo-N-ethyl)aniline
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Quality Control

Our 3-[[n-(3-Ethoxy-2,4,6-Triiodophenyl)-n-Ethylamino]Carbonyl]Propionic Acid is manufactured under strict quality systems. We provide material that meets the exacting standards required for pharmaceutical active substance intermediates, with a focus on purity and impurity profile control. A comprehensive Certificate of Analysis (COA) is supplied with each batch, detailing specifications such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Loss on Drying ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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