Description

3-[[n-(3-Ethoxy-2,4,6-Triiodophenyl)-n-Methylamino]Carbonyl]Propionic Acid is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. This high-purity intermediate is critical for ensuring the final pharmaceutical product's efficacy and safety profile. It is essential for manufacturers in the pharmaceutical and fine chemical industries developing non-ionic, low-osmolar contrast agents for diagnostic imaging.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of modern, non-ionic X-ray contrast agents like iopromide and iomeprol analogs.
• Contrast Media Research & Development: Used in R&D laboratories for developing new generations of iodinated contrast media with improved safety and imaging properties.
• Fine Chemical Synthesis: Serves as a precursor for other complex iodinated aromatic compounds used in various diagnostic applications.
• Radiology Agent Manufacturing: Employed in GMP-compliant production processes for injectable diagnostic formulations.

Basic Information

Product Name	3-[[n-(3-Ethoxy-2,4,6-Triiodophenyl)-n-Methylamino]Carbonyl]Propionic Acid
CAS No.	37938-65-1
Molecular Formula	C13H14I3NO4
Molecular Weight	672.97 g/mol
Synonyms	3-({[3-Ethoxy-2,4,6-triiodophenyl)(methyl)amino]carbonyl}propanoic acid; 3-[[(3-Ethoxy-2,4,6-triiodophenyl)-methylamino]carbonyl]propionic Acid; N-(3-Ethoxy-2,4,6-triiodophenyl)-N-methyl-3-carboxypropionamide; Iopromide Intermediate; Iomeprol Intermediate; Contrast Media Intermediate; 37938-65-1
EINECS	Contact for details

Quality Control

Our 3-[[n-(3-Ethoxy-2,4,6-Triiodophenyl)-n-Methylamino]Carbonyl]Propionic Acid is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. We provide comprehensive analytical data to support your regulatory filings, including impurity profiles and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing purity, identity, and specific tests. Our quality commitment aligns with ICH guidelines and supports customer requirements for GMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.