Description

Pentanoic Acid, 5-((3-Amino-2,4,6-Triiodophenyl)Ethylamino)-5-Oxo- (9C I) is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. This high-purity intermediate is critical for ensuring the final diagnostic agent's efficacy and safety profile. It is essential for pharmaceutical manufacturers and advanced research facilities developing next-generation non-ionic, low-osmolar contrast agents for enhanced patient tolerance and imaging clarity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of non-ionic X-ray contrast media, such as Iopamidol, Ioversol, and Iopromide analogs.
• Diagnostic Imaging Agent Synthesis: Used in the production of iodinated compounds for computed tomography (CT), angiography, and urography.
• Research & Development: Serves as a precursor in academic and industrial R&D for developing novel contrast agents with improved pharmacokinetics.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the triiodophenyl moiety into complex molecules.
• Quality Control Reference Standard: Can be utilized as a reference material for analytical method development and impurity profiling in contrast media production.

Basic Information

Product Name	Pentanoic Acid, 5-((3-Amino-2,4,6-Triiodophenyl)Ethylamino)-5-Oxo- (9C I)
CAS No.	37934-61-5
Molecular Formula	C13H16I3N2O3
Molecular Weight	635.99 g/mol
Synonyms	5-[(3-Amino-2,4,6-triiodophenyl)ethylamino]-5-oxopentanoic acid; 9C I (Contrast Agent Intermediate); N-[2-(3-Amino-2,4,6-triiodophenyl)ethyl]glutaramide acid; Iopamidol Intermediate 9C; Triiodinated Phenylalanine Derivative; 5-Oxo-5-[(3-amino-2,4,6-triiodophenyl)ethylamino]pentanoic acid; Contrast Media Precursor 9C-I
EINECS	Contact for details

Quality Control

Our Pentanoic Acid, 5-((3-Amino-2,4,6-Triiodophenyl)Ethylamino)-5-Oxo- (9C I) is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and related substances, to ensure compliance with ICH Q7 guidelines and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.