Description

2,4-Difluorobiphenyl is a high-purity fluorinated aromatic compound serving as a critical building block in advanced organic synthesis. This compound matters for its role in introducing fluorine atoms and biphenyl scaffolds, which are essential for modulating the electronic properties, metabolic stability, and binding affinity of target molecules. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and liquid crystal material industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the difluorobiphenyl moiety enhances biological activity.
• Liquid Crystal Materials: Serves as a core structure in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials and host materials in OLED devices.
• Polymer Chemistry: Employed as a monomer or modifier to create specialty polymers with enhanced thermal and chemical resistance.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.

Basic Information

Product Name	2,4-Difluorobiphenyl
CAS No.	37847-52-2
Molecular Formula	C12H8F2
Molecular Weight	190.19 g/mol
Synonyms	1,3-Difluoro-4-phenylbenzene; 2,4-Difluoro-1,1'-biphenyl; Biphenyl, 2,4'-difluoro-; 4-Phenyl-1,3-difluorobenzene; (2,4-Difluorophenyl)benzene
EINECS	Contact for details

Quality Control

Our 2,4-Difluorobiphenyl is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.