Description

Cyclopentanecarbonitrile, 1-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci) is a high-purity, protected cyanohydrin derivative used as a critical chiral building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the synthesis of pharmaceuticals and fine chemicals where stereochemical control is paramount. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized cyclopentane motifs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific stereochemistry for efficacy.
• Fine Chemical Production: Serves as a versatile precursor for synthesizing complex natural products, flavors, and fragrances.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic methodologies.
• Material Science: Potential monomer or intermediate for creating specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Cyclopentanecarbonitrile, 1-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci)
CAS No.	37802-93-0
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	1-(Tetrahydro-2H-pyran-2-yloxy)cyclopentanecarbonitrile; 1-(Tetrahydropyran-2-yloxy)cyclopentanecarbonitrile; 1-(THP-Oxy)cyclopentanecarbonitrile; Cyclopentanecarbonitrile, 1-[(tetrahydro-2H-pyran-2-yl)oxy]-; 1-(Oxan-2-yloxy)cyclopentane-1-carbonitrile; 1-(Tetrahydro-2H-pyran-2-yloxy)cyclopentanenitrile; 37802-93-0; 9CI
EINECS	Contact for details

Quality Control

Our Cyclopentanecarbonitrile, 1-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized by NMR, HPLC, and GC analysis to confirm identity, purity, and enantiomeric excess where applicable. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged procedures to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.