Description

2-Butenoic Acid, 4-Fluoro-, (2E)- is a high-purity fluorinated derivative of crotonic acid, characterized by its specific (E)-configuration and a fluorine substituent at the 4-position. This unique structure makes it a valuable building block for synthesizing more complex molecules in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom can enhance biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and coatings with tailored surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, Michael additions, and other transformations to introduce a fluorinated α,β-unsaturated carboxylic acid moiety.
• Ligand and Catalyst Development: Useful for preparing novel fluorinated ligands for metal complexes used in catalytic processes.

Basic Information

Product Name	2-Butenoic Acid, 4-Fluoro-, (2E)-
CAS No.	37759-72-1
Molecular Formula	C4H5FO2
Molecular Weight	104.08 g/mol
Synonyms	(E)-4-Fluorobut-2-enoic Acid; trans-4-Fluorocrotonic Acid; 4-Fluoro-trans-crotonic Acid; (2E)-4-Fluorobut-2-enoic Acid; 4-Fluoro-2-butenoic Acid, (E)-; 4-Fluorocrotonic Acid; (E)-4-Fluoro-2-butenoic Acid; Fluorocrotonic Acid
EINECS	Contact for details

Quality Control

Our 2-Butenoic Acid, 4-Fluoro-, (2E)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
(E)-Isomer Content	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.