Description

Oxacillin Penillic Acid is a key chemical intermediate and degradation product derived from the β-lactam antibiotic oxacillin. Its primary commercial value lies in its role as a critical reference standard and precursor in pharmaceutical research, development, and quality control processes. This compound is essential for manufacturers and analytical laboratories in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity materials for synthesis, impurity profiling, and method validation.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of oxacillin and its related substances in compliance with pharmacopeial monographs (USP, EP, JP).
• Impurity Profiling: Serves as a critical impurity marker in the stability testing and quality assurance of oxacillin sodium active pharmaceutical ingredient (API) and finished drug products.
• Research & Development: Employed as a building block or intermediate in the synthetic pathway for novel β-lactam compounds or for metabolic studies.
• Analytical Method Development: Utilized to validate and calibrate analytical methods such as High-Performance Liquid Chromatography (HPLC) and mass spectrometry for antibiotic analysis.
• Biochemical Research: Applied in studies investigating the degradation pathways, stability, and inactivation mechanisms of penicillin-class antibiotics.

Basic Information

Product Name	Oxacillin Penillic Acid
CAS No.	37699-31-3
Molecular Formula	C19H19N3O5S
Molecular Weight	401.44 g/mol
Synonyms	(2S,5R,6R)-6-[[(3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; 5-Methyl-3-o-chlorophenyl-4-isoxazolyl Penicillanic Acid; Oxacillin Penilloic Acid; Oxacillin Penicilloic Acid; BRL-1400 Penillic Acid; Phenylmethyl Penicillanic Acid Derivative
EINECS	Contact for details

Quality Control

Our Oxacillin Penillic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR and NMR, purity assay by HPLC, and control of specific impurities, to ensure it meets the stringent requirements for pharmaceutical reference standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.