Description

3-Bromo-2,2-Dimethylpropanenitrile is a versatile brominated nitrile building block, valued for its unique sterically hindered structure. This compound is essential for introducing the 2,2-dimethyl-3-bromopropyl moiety into target molecules, enabling the synthesis of complex intermediates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in organic synthesis and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly those requiring sterically hindered nitrile or carboxylic acid derivatives.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its bromine atom serves as a reactive handle for further functionalization.
• Ligand and Catalyst Precursor: Employed in the synthesis of specialized ligands for metal-catalyzed reactions and organocatalysts.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Organic Synthesis Building Block: Utilized in various name reactions, such as nucleophilic substitution and cyanoalkylation, to construct complex molecular architectures.
• Material Science Research: Investigated for the development of advanced organic materials, including liquid crystals and nonlinear optical materials.

Basic Information

Product Name	3-Bromo-2,2-Dimethylpropanenitrile
CAS No.	37647-55-5
Molecular Formula	C5H8BrN
Molecular Weight	162.03 g/mol
Synonyms	2,2-Dimethyl-3-bromopropanenitrile; 3-Bromo-2,2-dimethylpropionitrile; (Bromomethyl)isobutyronitrile; 3-Bromo-2,2-dimethylpropanenitrile; 2,2-Dimethyl-3-bromopropionitrile; 3-Bromo-2,2-dimethylpropane nitrile; Bromoneopentanenitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,2-Dimethylpropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.