Description

(R,S)-n-Nitrosoanabasine is a nitrosamine derivative of the alkaloid anabasine. This compound is of significant interest in chemical research and development, particularly in the study of nitrosamine chemistry and its implications. It serves as a critical intermediate or reference standard for analytical laboratories and R&D departments in the pharmaceutical, agrochemical, and toxicology sectors requiring high-purity specialty chemicals.

Application

• Analytical Reference Standard: Used as a certified standard for the identification and quantification of nitrosamine impurities in pharmaceutical products and complex matrices.
• Chemical Research Intermediate: Serves as a key synthetic building block or precursor in organic synthesis and medicinal chemistry research programs.
• Toxicological Studies: Employed in laboratory studies to investigate the metabolism, genotoxicity, and carcinogenic potential of nitrosamine compounds.
• Method Development & Validation: Essential for developing and validating sensitive analytical methods (e.g., GC-MS, LC-MS/MS) for nitrosamine detection.
• Quality Control & Assurance: Used by quality control laboratories to calibrate equipment and ensure analytical accuracy for nitrosamine screening.
• Regulatory Compliance Testing: Supports compliance testing for regulatory bodies like the FDA and EMA concerning nitrosamine impurities in APIs and finished drug products.

Basic Information

Product Name	(R,S)-n-Nitrosoanabasine
CAS No.	37620-20-5
Molecular Formula	C10H13N3O
Molecular Weight	191.23 g/mol
Synonyms	N-Nitrosoanabasine; 3-(1-Nitroso-2-piperidinyl)pyridine; 1-Nitroso-2-(3-pyridyl)piperidine; Anabasine, N-nitroso-; DL-N-Nitrosoanabasine; rac-N-Nitrosoanabasine; (±)-N-Nitrosoanabasine
EINECS	Contact for details

Quality Control

Our (R,S)-n-Nitrosoanabasine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for analytical reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.