Description

Methyl 2,3-Bis-o-Diphenylphosphino-4,6-o-Benzylideneglucopyranoside is a sophisticated chiral phosphine ligand, a critical component in asymmetric catalysis. Its value lies in enabling highly selective and efficient transition metal-catalyzed reactions, which are essential for producing enantiomerically pure pharmaceutical intermediates and fine chemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as asymmetric hydrogenation and cross-coupling reactions.

Application

• Asymmetric Hydrogenation Catalysis: A key ligand for producing chiral amines, amino acids, and other high-value intermediates with high enantiomeric excess (ee).
• Pharmaceutical Intermediate Synthesis: Used in the development and scale-up of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Cross-Coupling Reactions: Facilitates metal-catalyzed C-C and C-X bond formations under mild conditions for complex molecule assembly.
• Agrochemical Research: Employed in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Fine Chemical Production: Enables the manufacture of specialty flavors, fragrances, and advanced materials with precise stereocontrol.

Basic Information

Item	Detail
Product Name	Methyl 2,3-Bis-o-Diphenylphosphino-4,6-o-Benzylideneglucopyranoside
CAS No.	37605-43-9
Molecular Formula	C39H37O6P2
Molecular Weight	654.66 g/mol
Synonyms	Methyl 4,6-O-Benzylidene-2,3-bis-O-(diphenylphosphino)-α-D-glucopyranoside; Benzylidene-protected DIPHOS-Glucoside; Chiral Diphosphine Ligand; (R,R)- or (S,S)-DIPAMP-type glucopyranoside ligand; Methyl 2,3-di-O-(diphenylphosphino)-4,6-O-[(R)- or (S)-benzylidene]-α-D-glucopyranoside; Chiraphos-type sugar ligand; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of our Methyl 2,3-Bis-o-Diphenylphosphino-4,6-o-Benzylideneglucopyranoside undergoes rigorous analytical testing to ensure high purity and consistent performance in catalytic applications. Our quality protocols are designed to meet the stringent requirements of process chemistry and R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and spectroscopic data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air or moisture will degrade its catalytic efficacy.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee (specify isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.