Description

Methanesulfonamide, 1,1,1-Trifluoro-n-(3-Methylphenyl)- is a specialized fluorinated sulfonamide derivative, a key building block in advanced organic synthesis. This compound matters for its role in introducing the trifluoromethylsulfonamide (triflylamide) moiety, which can significantly alter the physical, chemical, and biological properties of target molecules. It is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Active Ingredient Development: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials with specific thermal or chemical resistance properties.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Life Science Reagent: Utilized in biochemical research as a tool compound for studying enzyme inhibition or protein interactions.
• Custom Synthesis and Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	Methanesulfonamide, 1,1,1-Trifluoro-n-(3-Methylphenyl)-
CAS No.	37595-72-5
Molecular Formula	C9H8F3NO2S
Molecular Weight	251.22 g/mol
Synonyms	N-(3-Methylphenyl)-1,1,1-trifluoromethanesulfonamide; 1,1,1-Trifluoro-N-(m-tolyl)methanesulfonamide; 3-Methylphenyl(trifluoromethyl)sulfonyl amine; m-Tolyl trifluoromethanesulfonamide; Trifluoromethanesulfonanilide, 3'-methyl-; α,α,α-Trifluoro-N-(3-methylphenyl)methanesulfonamide; N-m-Tolyltrifluoromethanesulfonamide
EINECS	Contact for details

Quality Control

Our Methanesulfonamide, 1,1,1-Trifluoro-n-(3-Methylphenyl)- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.