Description

6-n-Phtholyl-2-n-Z-L-Lysine is a specialized, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating the controlled construction of complex peptides and other bioactive molecules, ensuring high purity and regioselectivity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, peptide-based drugs, and biochemical probes.

Application

• Peptide Synthesis: As a key intermediate in solid-phase and solution-phase peptide synthesis (SPPS), particularly for introducing lysine residues with orthogonal protecting groups.
• Pharmaceutical Research: Used in the research and development of peptide-based pharmaceuticals, hormone analogs, and enzyme inhibitors.
• Bioconjugation: Serves as a linker or spacer molecule in the conjugation of peptides to other biomolecules, dyes, or solid supports for diagnostic and therapeutic applications.
• Chemical Biology: Employed in the synthesis of labeled peptides and protein fragments for studying protein-protein interactions and cellular processes.
• Protecting Group Chemistry: Utilized in methodologies requiring the selective protection and deprotection of amino acid side chains during multi-step synthetic sequences.
• Academic & Industrial R&D: A valuable reagent for synthetic chemistry laboratories in both academic settings and industrial R&D departments focused on medicinal chemistry.

Basic Information

Product Name	6-n-Phtholyl-2-n-Z-L-Lysine
CAS No.	37579-45-6
Molecular Formula	C21H24N2O5
Molecular Weight	384.43 g/mol
Synonyms	N6-Phthaloyl-N2-carbobenzoxy-L-lysine; N6-Phthaloyl-N2-Cbz-L-lysine; N6-Phthaloyl-N2-Z-L-lysine; Z-Lys(N-Phth)-OH; (S)-2-(((Benzyloxy)carbonyl)amino)-6-(1,3-dioxoisoindolin-2-yl)hexanoic acid; Nα-Carbobenzoxy-Nε-phthaloyl-L-lysine; Nα-Z-Nε-Phth-L-lysine
EINECS	Contact for details

Quality Control

Our 6-n-Phtholyl-2-n-Z-L-Lysine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.