Description

7-Amino-3-(1,2,3-Triazol-4-Ylthio)Methyl Cephalosporanic Acid is a key advanced pharmaceutical intermediate, specifically a cephalosporin nucleus, used in the synthesis of modern antibiotics. Its value lies in providing the core structural framework for developing potent, broad-spectrum cephalosporin drugs with enhanced stability and efficacy. This high-purity intermediate is essential for pharmaceutical manufacturers and R&D facilities focused on antibiotic development and production. The compound, with CAS No. 37539-03-0, is critical for ensuring the quality and consistency of the final active pharmaceutical ingredient (API).

Application

• Synthesis of Advanced Cephalosporin Antibiotics: Serves as a crucial building block for third and fourth-generation cephalosporin APIs.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for designing and testing new antibiotic candidates with improved pharmacological profiles.
• Active Pharmaceutical Ingredient (API) Manufacturing: A key intermediate in the multi-step synthesis of finished antibiotic drugs.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes for commercial-scale, cost-effective production of cephalosporins.
• Reference Standard: Can be utilized as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Item	Details
Product Name	7-Amino-3-(1,2,3-Triazol-4-Ylthio)Methyl Cephalosporanic Acid
CAS No.	37539-03-0
Molecular Formula	C12H13N5O4S2
Molecular Weight	339.39 g/mol
Synonyms	7-ACA Triazole Derivative; 7-Aminocephalosporanic Acid Triazole Thioether; (6R,7R)-7-Amino-3-[(1H-1,2,3-triazol-4-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; 7-ATCA; Cephalosporin C Nucleus Triazole; 7-ACA-3-Triazolylthiomethyl; ATCA
EINECS	Contact for details

Quality Control

Our 7-Amino-3-(1,2,3-Triazol-4-Ylthio)Methyl Cephalosporanic Acid is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and quality assurance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.