Description

Pipotiazine Palmitate is a long-acting ester prodrug of the typical antipsychotic agent pipotiazine. This compound is of significant commercial and pharmaceutical importance as it enables sustained release of the active moiety, pipotiazine, following intramuscular injection. It is primarily utilized in the formulation of long-acting injectable (LAI) antipsychotic medications for the management of chronic psychotic disorders such as schizophrenia. The extended duration of action provided by the palmitate ester improves patient compliance and stabilizes therapeutic outcomes.

Application

• Active Pharmaceutical Ingredient (API) for long-acting injectable antipsychotic formulations.
• Pharmaceutical Intermediates in the synthesis of specialized neuroleptic drug products.
• Research & Development for novel drug delivery systems targeting central nervous system disorders.
• Reference Standard for analytical method development and quality control in pharmaceutical laboratories.
• Contract Manufacturing for generic and specialty pharmaceutical companies.

Basic Information

Product Name	Pipotiazine Palmitate
CAS No.	37517-26-3
Molecular Formula	C35H53N3O2S2
Molecular Weight	619.94 g/mol
Synonyms	Piportil Palmitate; Pipotiazine Palmitate Ester; 10-[3-[4-(2-Hydroxyethyl)piperidino]propyl]-N,N-dimethylphenothiazine-2-sulfonamide Palmitate; 2-Pyrrolidinone, 1-[3-[4-(2-hydroxyethyl)-1-piperidinyl]propyl]-10H-phenothiazin-2-yl]-, palmitate; Pipotiazin Palmitate
EINECS	Contact for details

Quality Control

Our Pipotiazine Palmitate is manufactured under strict quality management systems. It undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical development. We provide full traceability and support regulatory submissions. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.