Description

[3-(1-Ethoxyethoxy)Propyl]Lithium is a highly reactive organolithium compound used as a key building block in advanced organic synthesis. This compound matters for its ability to introduce the functionalized 3-(1-ethoxyethoxy)propyl group into target molecules, enabling the creation of complex chemical architectures. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries for the development of new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate Synthesis: Used as a nucleophilic reagent for the introduction of protected hydroxyalkyl chains in the synthesis of novel drug candidates.
• Agrochemical Active Ingredient Development: Serves as a key reagent for constructing complex molecular scaffolds in herbicide and fungicide research.
• Specialty Polymer & Material Science: Employed in anionic polymerization and as a functional initiator to create polymers with specific side-chain functionalities.
• Liquid Crystal & OLED Material Production: Acts as a critical synthon for building advanced organic electronic materials and display components.
• Fine Chemical & Catalyst Ligand Synthesis: Utilized in the preparation of sophisticated ligands for asymmetric catalysis and other fine chemicals.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new reaction pathways in synthetic organic chemistry.

Basic Information

Product Name	[3-(1-Ethoxyethoxy)Propyl]Lithium
CAS No.	37494-03-4
Molecular Formula	C7H15LiO2
Molecular Weight	138.13 g/mol
Synonyms	1-Lithio-3-(1-ethoxyethoxy)propane; 3-(1-Ethoxyethoxy)propyllithium; (1-Ethoxyethoxy)propyllithium; 3-(1-Ethoxyethoxy)prop-1-yllithium; Lithium [3-(1-ethoxyethoxy)propyl]; Acetal-protected 3-hydroxypropyllithium reagent; 3-(α-Ethoxyethoxy)propyllithium
EINECS	Contact for details

Quality Control

Our [3-(1-Ethoxyethoxy)Propyl]Lithium is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and concentration, typically supplied as a solution in a specified hydrocarbon solvent. Certificates of Analysis (COA) detailing assay (by titration), solvent content, and impurity profile are provided to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. Due to its moisture-sensitive and pyrophoric nature, the container must be kept sealed and handled only under anhydrous conditions using appropriate techniques.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms
Assay (Titration)	0.5 M in cyclohexane (or specified solvent)
Purity	≥ 95% (by NMR)
Solvent Content	Balance
Water Content (KF)	< 50 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.