Description

19-Iodocholesterol is a halogenated derivative of cholesterol, a key intermediate in the synthesis of various steroid-based compounds. This compound is particularly valuable for introducing a radioactive iodine label (e.g., I-125) into cholesterol molecules for research and diagnostic applications. It serves as a critical building block for pharmaceutical R&D, especially in the fields of endocrinology, lipid metabolism studies, and the development of radiopharmaceuticals.

Application

• Radiopharmaceutical Precursor: Primary use as a precursor for synthesizing iodine-125 labeled cholesterol analogs used in diagnostic imaging and research.
• Biochemical Research: Used as a tracer or probe in studies of cholesterol absorption, metabolism, and membrane biology.
• Steroid Synthesis Intermediate: A versatile intermediate for the chemical modification and synthesis of novel steroid derivatives with potential therapeutic activity.
• Reference Standard: Serves as a high-purity analytical standard in chromatography (HPLC, GC) for method development and quality control in pharmaceutical analysis.
• Metabolic Pathway Studies: Employed in laboratory investigations to track and understand specific biochemical pathways involving sterols.

Basic Information

Product Name	19-Iodocholesterol
CAS No.	37414-03-2
Molecular Formula	C27H45IO
Molecular Weight	512.46 g/mol
Synonyms	19-Iodo-5-cholesten-3β-ol; 3β-Hydroxy-19-iodocholest-5-ene; 19-Iodocholest-5-en-3β-ol; Cholest-5-en-3β-ol, 19-iodo-; 19-Iodo-cholesterol; 19-I-Cholesterol; 19-Iodo-3β-hydroxycholest-5-ene
EINECS	Contact for details

Quality Control

Our 19-Iodocholesterol is manufactured under strict quality control protocols to ensure high chemical purity and consistency. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.