Description

Creatinine Deiminase is a highly specific hydrolytic enzyme that catalyzes the conversion of creatinine to N-methylhydantoin and ammonia. This precise biocatalytic activity makes it an indispensable reagent for the accurate quantification of creatinine in clinical and research settings. It is primarily utilized by diagnostic manufacturers, clinical laboratories, and life science research institutions for developing enzymatic assays and biosensors.

Application

• Clinical Diagnostic Kits: Core component in enzymatic creatinine assay kits for serum, plasma, and urine analysis in automated clinical chemistry analyzers.
• Point-of-Care Testing (POCT): Used in the development of portable biosensors and test strips for rapid renal function assessment.
• Biochemical Research: Essential tool for studying purine metabolism, renal physiology, and muscle metabolism in academic and pharmaceutical research.
• Veterinary Diagnostics: Employed in veterinary medicine for assessing kidney function in companion and livestock animals.
• Food & Beverage Analysis: Potential application in analyzing creatinine levels in meat products as an indicator of quality or thermal processing.
• Reagent Manufacturing: Sourced by chemical suppliers for the formulation of high-purity enzymatic reagents and calibration standards.

Basic Information

Product Name	Creatinine Deiminase
CAS No.	37289-15-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Creatinine Amidohydrolase; Creatinine Hydrolase; Creatinine Iminohydrolase; Microbial Creatininase; EC 3.5.4.21; CD; CRD
EINECS	Contact for details

Quality Control

Our Creatinine Deiminase is produced under stringent quality management systems. Each batch undergoes comprehensive testing for specific activity, purity, and stability to ensure consistent performance in diagnostic applications. Certificates of Analysis (COA) detailing assay results, including activity units/mg protein and contaminant levels, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms
Specific Activity	≥ 50 U/mg protein
Protein Content (Biuret)	≥ 90%
pH (in solution)	6.5 - 7.5
Loss on Drying	≤ 5.0 %
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.