Description

Hyaluronidaseexleech CAS NO 37288-34-9 is a high-purity enzyme preparation derived from leech sources, primarily used to degrade hyaluronic acid. This product is critical for enhancing the dispersion and absorption of other co-administered drugs or fluids in medical and research applications. It is an essential reagent for pharmaceutical manufacturers, biotechnology research laboratories, and diagnostic kit producers requiring controlled enzymatic activity.

Application

• Pharmaceutical Adjuvant: Used to increase the absorption and dispersion of locally injected drugs, anesthetics, or fluids.
• Ophthalmic Surgery: Facilitates the spread of local anesthetics and helps in the management of vitreous hemorrhage.
• Dermatology & Aesthetics: Employed as an antidote to correct complications from hyaluronic acid-based dermal fillers.
• Research & Diagnostic Reagent: Serves as a key enzyme in biochemical research for studying glycosaminoglycans and in vitro diagnostic assays.
• Tissue Dissociation: Aids in the preparation of cell cultures by breaking down the extracellular matrix.
• Enhancement of Subcutaneous Infusions: Used in hypodermoclysis to improve the absorption of subcutaneous fluids.

Basic Information

Product Name	Hyaluronidaseexleech
CAS No.	37288-34-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hyaluronidase (Leech); Hyaluronoglucosaminidase; Spreading Factor; Hyaluronate Lyase; Hyaluronidase Ex Leech; Lydase; Alidase; Wydase; Ronidase; Vitrase
EINECS	Contact for details

Quality Control

Our Hyaluronidaseexleech is manufactured under strict quality systems. Each batch undergoes rigorous testing for potency, purity, and sterility where applicable, ensuring compliance with relevant pharmacopoeial standards (e.g., USP, EP) for enzyme activity. Certificates of Analysis (COA) documenting specific activity, protein content, and absence of specified impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, keep the container in a dry, cool environment and avoid repeated temperature fluctuations.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (IR)	Conforms
Assay (Enzymatic Activity)	≥ 300 USP units/mg (or as per grade)
Protein Content (Biuret)	Reported on COA
pH (in solution)	5.0 - 7.5
Loss on Drying	≤ 5.0 %
Bacterial Endotoxins	< 0.1 EU/Unit (for injectable grades)
Microbial Limits	Meets Ph. Eur. 2.6.12 / USP <61> (as per grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.