Description

Factor D, Human CAS NO 37213-56-2 is a purified human complement system protein, also known as adipsin, which plays a critical role in the alternative pathway of complement activation. This high-purity biological reagent is essential for research and development in immunology, drug discovery, and diagnostic assay development. It is primarily utilized by pharmaceutical companies, biotechnology research laboratories, and diagnostic manufacturers focused on inflammatory diseases, autoimmune disorders, and complement-targeted therapeutics.

Application

• Biomedical Research: Used as a key reagent in studying the alternative complement pathway, enzyme kinetics, and immune system regulation.
• Drug Discovery & Screening: Serves as a target protein for the development and validation of novel therapeutic inhibitors for inflammatory and autoimmune conditions.
• Diagnostic Development: Employed as a standard or calibrator in the manufacturing of immunoassays and clinical diagnostic kits for complement deficiency or overactivation.
• Biologics Production: Acts as a critical raw material or reference standard in the quality control of biopharmaceuticals that interact with the complement system.
• Academic Research: Facilitates fundamental studies in immunology, molecular biology, and pathophysiology related to metabolic and inflammatory diseases.

Basic Information

Product Name	Factor D, Human
CAS No.	37213-56-2
Molecular Formula	C~1900H~3000N~500O~600S~20
Molecular Weight	~24 kDa
Synonyms	Complement Factor D; Adipsin; C3 Convertase Activator; Properdin Factor D; CFD; DF; Complement Factor D (Human); Adipsin (Human); Serine Protease Factor D; EC 3.4.21.46
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for biological reagents. Each batch is characterized for identity, purity, and functional activity. Certificates of Analysis (COA) are available upon request, providing detailed results for parameters such as purity by SDS-PAGE, functional activity assay, endotoxin levels, and sterility where applicable.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Single band at ~24 kDa
Purity (HPLC)	≥ 95%
Protein Content	≥ 90% (Biuret)
Specific Activity	Contact for details
Endotoxin	< 1.0 EU/μg
Solubility	Soluble in water or specified buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.